How do you replace the injectors and Fuel Rail in your Cadillac Escalade?

To replace your vehicle's fuel injectors and O-rings, relieve fuel system pressure and disconnect the battery. Remove the air intake duct and, for non-6.0L models, the intake manifold and fuel pump/rail insulator. Disconnect the fuel lines and injector electrical connectors, and remove the fuel rails and injectors. Remove the old Teflon seals and O-rings from each injector and clean the grooves. Install new seals and lubricate the new O-rings with engine oil. Reattach the injectors to the fuel rail, reinstall the rail, and secure it with new retainers. Apply thread locking compound to the fuel rail bolts before tightening. Reconnect the fuel lines, replace the fuel pressure sensor, and reassemble. For 6.0L models, remove the intake manifold cover and bracket, disconnect electrical connectors, detach the wiring harness, and disconnect the PCV hose.

Genuine Cadillac Escalade Fuel Rail

Engine Fuel Rail

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19 Fuel Rails found

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Cadillac Escalade Rail Assembly, Multiport Fuel Injection Fuel
Part Number: 12602113
$95.46 MSRP: $198.23
You Save: $102.77 (52%)
Ships in 1-2 Business Days
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Product Specifications
- Other Name: RAIL, Fuel Injection; Fuel Rail
- Replaces: 89017375
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2004-2006 Cadillac Escalade | 1/2 TON, 3/4 TON, EXT 1/2 TON, EXT 3/4 TON, YUKON/DENALI/ESCALADE | 8 Cyl 5.3L, 8 Cyl 6.0L
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Cadillac Escalade Rail, F/Injn Fuel
Part Number: 12707882
$97.82 MSRP: $203.12
You Save: $105.30 (52%)
Ships in 1-2 Business Days
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Product Specifications
- Other Name: Fuel Rail
- Replaced by: 12729464
- Replaces: 12684180, 12623129, 12659650, 12668400, 12685360, 12701132, 12669883
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2015-2021 Cadillac Escalade | 1/2 TON, 1500 4 DOOR, 1500 4 DOOR SUV, 1500 4 DOOR UTILITY, 1500 CREW CAB, 1500 CREW CAB STANDARD BOX, 4 DOOR 1/2 TON, CLASSIC 1500 CREW CAB LONG BOX, CLASSIC 1500 EXTENDED CAB STANDARD BOX, CLASSIC 1500 REGULAR CAB LONG BOX, CLASSIC 1500 REGULAR CAB STANDARD BOX, YUKON XL/DENALI XL/ESCALADE ESV, YUKON/DENALI/ESCALADE | 8 Cyl 6.2L
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Cadillac Escalade Rail Assembly, Sequential Multiport Fuel Injection Fuel
Part Number: 12660710
$153.61 MSRP: $318.96
You Save: $165.35 (52%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: RAIL, Fuel Injection; Fuel Rail
- Replaces: 12621665, 12621563
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2007-2008 Cadillac Escalade | 1/2 TON, EXT 1/2 TON, YUKON XL/DENALI XL/ESCALADE ESV, YUKON/DENALI/ESCALADE | 8 Cyl 6.2L
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Cadillac Escalade Rail Asm,Multiport Fuel Injection Fuel (Right Hand)
Part Number: 17113695
$134.22 MSRP: $278.67
You Save: $144.45 (52%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: RAIL, Fuel Injection; Fuel Rail
- Position: Passenger Side
- Replaces: 89017376
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2002-2006 Cadillac Escalade | 1/2 TON, 3/4 TON, EXT 1/2 TON, EXT 3/4 TON, YUKON/DENALI/ESCALADE | 8 Cyl 5.3L, 8 Cyl 6.0L
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Cadillac Escalade Rail Assembly, Sequential Multiport Fuel Injection Fuel
Part Number: 12660709
$162.28 MSRP: $306.18
You Save: $143.90 (47%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: RAIL, Fuel Injection; Fuel Rail
- Replaces: 12621668, 12621566
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2009-2013 Cadillac Escalade | YUKON/DENALI/ESCALADE | 8 Cyl 6.0L, 8 Cyl 6.0L Flex
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Cadillac Escalade Rail Assembly, Sequential Multiport Fuel Injection Fuel
Part Number: 12621663
$181.71 MSRP: $342.84
You Save: $161.13 (47%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: RAIL, Fuel Injection; Fuel Rail
- Replaces: 12621561
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2009-2013 Cadillac Escalade | 1/2 TON, EXT 1/2 TON, YUKON XL/DENALI XL/ESCALADE ESV, YUKON/DENALI/ESCALADE | 8 Cyl 6.2L Flex
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Cadillac Escalade Rail Assembly, High Press Dsl F/Injn
Part Number: 55505909
$168.04 MSRP: $302.78
You Save: $134.74 (45%)
Ships in 1-3 Business Days
ADD TO CART
Product Specifications
- Other Name: Fuel Rail
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2021 Cadillac Escalade | 1/2 TON, YUKON XL/DENALI XL/ESCALADE ESV, YUKON/DENALI/ESCALADE | 6 Cyl 3.0L Diesel
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Cadillac Escalade Rail, F/Injn Fuel
Part Number: 12701134
$97.82 MSRP: $203.12
You Save: $105.30 (52%)
Ships in 1-2 Business Days

Out of Stock
Product Specifications
- Other Name: Fuel Rail
- Replaced by: 12729466
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2015-2021 Cadillac Escalade | 1/2 TON, 1500 4 DOOR, 1500 4 DOOR SUV, 1500 4 DOOR UTILITY, 1500 CREW CAB, 1500 CREW CAB STANDARD BOX, 4 DOOR 1/2 TON, CLASSIC 1500 CREW CAB LONG BOX, CLASSIC 1500 EXTENDED CAB STANDARD BOX, CLASSIC 1500 REGULAR CAB LONG BOX, CLASSIC 1500 REGULAR CAB STANDARD BOX, YUKON XL/DENALI XL/ESCALADE ESV, YUKON/DENALI/ESCALADE | 8 Cyl 6.2L
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Cadillac Escalade Pipe Kit,Fuel Injection Fuel Return
Part Number: 89017381
Product Specifications
- Other Name: PIPE KIT, Fuel Line
- Replaces: 88894359
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2002-2004 Cadillac Escalade | EXT 1/2 TON, EXT 3/4 TON, YUKON/DENALI/ESCALADE | 8 Cyl 5.3L, 8 Cyl 6.0L
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Cadillac Escalade Pipe Kit,Fuel Injection Fuel Feed & Return
Part Number: 17113214
Product Specifications
- Other Name: PIPE KIT, Fuel Line
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2002-2004 Cadillac Escalade | EXT 1/2 TON, YUKON/DENALI/ESCALADE
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Cadillac Escalade Rail Asm,Multiport Fuel Injection Fuel (Left Hand)
Part Number: 17113696
Product Specifications
- Other Name: RAIL, Fuel Injection; Fuel Rail
- Position: Driver Side
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2002-2003 Cadillac Escalade | EXT 1/2 TON, EXT 3/4 TON, YUKON/DENALI/ESCALADE | 8 Cyl 5.3L, 8 Cyl 6.0L
View related parts
Cadillac Escalade Rail Asm,Multiport Fuel Injection Fuel
Part Number: 88894358
Product Specifications
- Other Name: RAIL, Fuel Injection
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2002-2004 Cadillac Escalade | EXT 1/2 TON, YUKON/DENALI/ESCALADE
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Cadillac Escalade Rail Asm,Direct Fuel Injection Fuel
Part Number: 97303659
Product Specifications
- Other Name: RAIL, Fuel Injection; Fuel Rail
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2004-2005 Cadillac Escalade | 3/4 TON, EXT 3/4 TON
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Cadillac Escalade Rail Asm,Direct Fuel Injection Fuel
Part Number: 97208075
Product Specifications
- Other Name: RAIL, Fuel Injection; Fuel Rail
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2002-2004 Cadillac Escalade | EXT 3/4 TON
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Cadillac Escalade Rail Kit,Multiport Fuel Injection Fuel
Part Number: 12575055
Product Specifications
- Other Name: RAIL KIT, Fuel Injection; Fuel Rail
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2002-2003 Cadillac Escalade | EXT 3/4 TON
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Cadillac Escalade Rail Assembly, Sequential Multiport Fuel Injection Fuel
Part Number: 12599737
Product Specifications
- Other Name: RAIL, Fuel Injection; Fuel Rail
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2005 Cadillac Escalade | 1/2 TON, EXT 1/2 TON, YUKON/DENALI/ESCALADE
View related parts
Cadillac Escalade Pipe Kit,Fuel Injection Fuel Feed & Return
Part Number: 17113204
Product Specifications
- Other Name: PIPE KIT, Fuel Line
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 1999-2000 Cadillac Escalade | 1 TON CREW CAB, 1/2 TON, 3/4 TON, 4 DOOR 1/2 TON, CLASSIC 4 DOOR 1/2 TON, CREW CAB 1 TON, EXTENDED CAB 1 TON, EXTENDED CAB 6'6" BOX 1/2 TON, EXTENDED CAB 6'6" BOX 3/4 TON, EXTENDED CAB 8' BOX 3/4 TON, K2500 CREW CAB, K3500 CAB CHASSIS 135.5, K3500 CAB CHASSIS 159.9, REGULAR CAB 1 TON, REGULAR CAB 3/4 TON, YUKON/DENALI/ESCALADE | 8 Cyl 5.7L
View related parts
Cadillac Escalade Rail Asm,Direct Fuel Injection Fuel
Part Number: 97303658
Product Specifications
- Other Name: RAIL, Fuel Injection; Fuel Rail
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2004-2005 Cadillac Escalade | 3/4 TON, EXT 3/4 TON
View related parts
Cadillac Escalade Rail Kit,Multiport Fuel Injection Fuel
Part Number: 12574941
Product Specifications
- Other Name: RAIL KIT, Fuel Injection; Fuel Rail
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following Vehicles:
- 2004-2005 Cadillac Escalade | 3/4 TON, EXT 3/4 TON

Cadillac Escalade Fuel Rail Parts Questions & Experts Answers

Rail, F/Injn Fuel
12707882
Q: How do you replace the injectors and Fuel Rail in your Cadillac Escalade?
A: To replace your vehicle's fuel injectors and O-rings, relieve fuel system pressure and disconnect the battery. Remove the air intake duct and, for non-6.0L models, the intake manifold and Fuel Pump/rail insulator. Disconnect the fuel lines and injector electrical connectors, and remove the fuel rails and injectors. Remove the old Teflon seals and O-rings from each injector and clean the grooves. Install new seals and lubricate the new O-rings with engine oil. Reattach the injectors to the fuel rail, reinstall the rail, and secure it with new retainers. Apply thread locking compound to the fuel rail bolts before tightening. Reconnect the fuel lines, replace the Fuel Pressure Sensor, and reassemble. For 6.0L models, remove the intake manifold cover and bracket, disconnect electrical connectors, detach the wiring harness, and disconnect the PCV hose.